Researchers discover a new cancer-driving mutation in the `dark matter` of the cancer genome
(World News Science)

October 9, 2019 Change in just one letter of DNA code in a gene conserved through generations of evolution can cause multiple types of cancer TORONTO - An Ontario-led research group has discovered a novel cancer-driving mutation in the vast non-coding regions of the human cancer genome, also known as the `dark matter` of human cancer DNA. The mutation, as described in two related studies published in Nature on October 9, 2019, represents a new potential therapeutic target for several types of cancer including brain, liver and blood cancer. This target could be used to develop novel treatments for patients with these difficult-to-treat diseases. `Non-coding DNA, which makes up 98 per cent of...