Chemists show that the catalytic range of enzymes can be enlarged
(PHYSorg.com Chemistry)

A team of chemists at the University of Manchester has found a way to incorporate an abnormal residue into an enzyme to show how the catalytic range of enzymes can be enlarged. In their paper published in the journal Nature, the group describes expanding the range of catalytic enzymes that could be used to provide a broader variety of side chains for catalysis-by using an extended `alphabet` of amino acids. Adam Nelson, with the University of Leeds, has published a News and Views Research paper discussing the work by the team in the same journal issue.