New immunotherapy targeting blood-clotting protein
(PHYSorg.com Medicine & Health)

Normally, the blood protein fibrin does not enter the brain. But in several neurological disorders, the blood-brain barrier-which keeps large molecules in the blood from entering the brain-becomes abnormally permeable, allowing fibrin to leak into the brain and trigger inflammation. Emerging evidence points to a leaky blood-brain barrier as an early event in brain diseases that causes neurodegeneration. In fact, this process may lead to the death of nerve cells in multiple sclerosis, Alzheimer`s disease, and other disorders.