Novel in vitro approaches for toxicity testing of inhaled substances
(PHYSorg.com Medicine & Health)

Integrated approaches that avoid the use of animals to assess the toxicity of inhaled materials may include a computational model to screen for chemical reactivity, a human tissue-based assay to predict the absorption of a chemical into the respiratory tract, and other types of advanced systems based on in vitro and in vivo respiratory biology. A comprehensive review of the progress and ongoing efforts in this fascinating field is the focus of a new special issue on Inhalation Toxicity Testing published in Applied In Vitro Toxicology. The issue is available free on the Applied In Vitro Toxicology website.