Role of transcriptional co-factor hints at possible inflammatory bowel disease treatment
(PHYSorg.com Medicine & Health)

Inflammatory bowel disease (IBD), including the two conditions ulcerative colitis and Crohn`s disease, results in long-term inflammation of the gut and is associated with dysregulation of the immune system. However, it is notoriously difficult to determine the cause of IBD, although genetic and environmental factors are implicated. To better understand disease development, researchers have developed a mouse model in which gut inflammation is induced by addition of the chemical dextran sodium sulfate (DSS) to the drinking water of mice.