Physicists use mathematical algorithms to examine experimental 3-D structures of chromosomes
(PHYSorg.com Chemistry)

Everyone knows that long bits of yarn, or charging cables and the like, tend to get quickly tangled and form nasty knots. Little is known about the structures of our genetic material, chromosomes, which also consist of long strings that-according to our experience-should be likely to become knotted. However, up to now it has not been possible to study this experimentally.