Major Progress Made in Plant Multivesicular Body Biogenesis and Membrane Protein Vacuolar Transport by CUHK Researchers Providing New Insight into Improving Crop Quality
(WorldNews Asia)

A team of researchers at The Chinese University of Hong Kong (CUHK) led by Professor JIANG Liwen, Choh-Ming Li Professor of Life Sciences, has recently made a major breakthrough in revealing in plants a unique negative regulator for plant Multivesicular Body (MVB)/Prevacuolar compartment (PVC) biogenesis and membrane proteins vacuolar transport. The team has newly identified a novel role and mechanism for plant-specific BRAF (BRo1-domain protein as FREE1 suppressor), which functions as a unique evolutionary endosomal sorting complex required for transport (ESCRT) negative regulator in orchestrating intraluminal vesicle (ILV) formation in MVB/PVCs and the sorting of membrane proteins for...