Takeda Receives Positive CHMP Opinion Recommending ALUNBRIG® (brigatinib) for the Treatment of ALK+ Non-Small Cell Lung Cancer in Patients Previously Treated with Crizotinib
(WorldNews Japan)

- Opinion Based on Pivotal Phase 2 ALTA Trial, in which ALUNBRIG Demonstrated an Objective Response Rate of 56% and Longest Reported Median Progression-Free Survival of 16.7 months in the Post-Crizotinib Setting Cambridge, Mass. and Osaka, Japan, September 21, 2018 - Takeda Pharmaceutical Company Limited (TSE: 4502) today announced that the European Medicines Agency`s (EMA) Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion, recommending the full approval of ALUNBRIG® (brigatinib) as a monotherapy for the treatment of adult patients with anaplastic lymphoma kinase-positive (ALK+) advanced non-small cell lung cancer (NSCLC) previously treated with crizotinib....