CUHK Study Reveals Novel Mechanism that Contributes to Vascular Endothelial Dysfunction in Diabetes
(WorldNews China)

A research team led by Prof. Huang Yu of the School of Biomedical Sciences and Director of the Institute of Vascular Medicine, Faculty of Medicine at The Chinese University of Hong Kong (CUHK), has recently revealed a cell-to-cell communication mechanism that contributes to vascular endothelial dysfunction in diabetes. Based on the studies made on diabetic mice, the team has found that an enzyme `arginase 1` was enriched in serum exosomes and transferred to endothelial cells, thus impairing endothelial function. The finding has been published in Proceedings of the National Academy of Sciences (PNAS). One in ten people in Hong Kong has type II diabetes mellitus. Long-term high...