Applications toward new treatments for cancer, other d...
(WorldNews Japan)

Graduate School of Pharmaceutical Sciences / Faculty of Pharmaceutical Sciences 2017/08/17 Researchers at the University of Tokyo have developed an artificial catalyst system that selectively modifies chromatin-the substance in cells that forms chromosomes-through a chemical modification known as acetylation, which is critical to proteins. Moreover, synthetic acetylation of nucleosomes, the basic units of chromosomes, by this catalyst system without relying on enzymes, points to the possibility of promoting gene transcription artificially. A nucleosome consists of chromosome-forming...