Bioengineering biomimetic human small muscular pulmonary arteries
(PHYSorg.com Biology)

During the progression of pulmonary hypertension, structural and functional changes in the small muscular arteries play a significant role and contribute to the disease. Bioengineers aim to develop advanced, anatomically biomimetic in vitro models of microvessels, since non-human vessels are not an accurate representation of the human microvascular architecture and microenvironment. In a new report now on Science Advances, Qianru Jin and a multidisciplinary research team at the Johns Hopkins University, U.S., described a new method for parallel biofabrication of a photopatterned, self-rolled and biomimetic pulmonary arterial microvessel of adjustable size and architecture.