Melting reveals drug targets in a living organism
(PHYSorg.com Biology)

Developing new medicines and understanding how they target specific organs often gives a crucial advantage in the fight against human diseases. An international team led by researchers at the European Molecular Biology Laboratory and Cellzome, a GSK company, has developed a technology to systematically identify drug targets in living animals. In their results, published in Nature Biotechnology on 20 January, the scientists mapped protein-drug interactions in rat organs and blood. Their research opens pathways in drug discovery, fundamental biology, and personalized medicine.