New technology for protein bioconjugation and structural proteomics
(PHYSorg.com Chemistry)

Researchers at the Czech Academy of Sciences and the Brno-based start-up CF Plus Chemicals, a spin-off of ETH Zurich, has reported a new technology called CF LINK for site-selective bioconjugation of proteins and their structural characterization. The technology can selectively prepare protein conjugates via their tryptophan residues and perform post-translational modification of aromatic amino acids. Furthermore, it can also be used as a tool for the mapping of protein surfaces and studies of protein-protein interactions.