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RSS FeedsBridgeBio and Eidos Present Data from Phase 2 Open Label Extension Suggesting Long-term Tolerability of AG10 and Stabilization of Transthyretin Amyloid Cardiomyopathy Disease Measures
(WorldNews Health)

 
 

17 november 2019 02:00:05

 
BridgeBio and Eidos Present Data from Phase 2 Open Label Extension Suggesting Long-term Tolerability of AG10 and Stabilization of Transthyretin Amyloid Cardiomyopathy Disease Measures
(WorldNews Health)
 




AG10 was Well Tolerated with Median 65 Weeks Follow-up since Phase 2 Initiation Rates of All-Cause Mortality (Including Either Death or Cardiac Transplantation, 8.5%) and Cardiovascular Hospitalization (25.5%) Observed in Exploratory Analysis Were Lower than Rates Observed in Placebo-treated Participants in the ATTR-ACT Study Near-complete Stabilization of TTR Maintained in Participants Throughout Duration of Study Serum TTR levels, a Prognostic Indicator of Survival in ATTR-CM Patients, Were Elevated and Maintained in the Normal Range Throughout the Study Duration Cardiac Biomarkers and Echocardiographic Parameters Were Stable Throughout Trial Duration Presentation from AHA 2019 Scientific...
 
26 viewsCategory: Science > Medicine
 
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