Randomized Comparison of Early Surgery Versus Conventional Treatment in Very Severe Aortic Stenosis
(WorldNews Health)

Contribution To Literature: The RECOVERY trial showed that early surgery among patients with asymptomatic but very severe aortic stenosis results in improved survival out to 8 years compared with watchful waiting. Description: The goal of the trial was to assess the safety and benefit of surgery vs. watchful waiting among patients with asymptomatic very severe aortic stenosis. Study Design Eligible patients with very severe asymptomatic aortic stenosis were randomized in a 1:1 open-label fashion to either early surgical aortic valve replacement (AVR) (n = 4,089) or watchful waiting (n = 4,090). Total screened: 273 Total number of enrollees: 145 Duration of follow-up: 6.2 years Mean patient...