Colchicine Cardiovascular Outcomes Trial
(World News USA)

Contribution To Literature: The COLCOT trial showed that colchicine was effective at preventing major adverse cardiac events after a myocardial infarction. Description: The goal of the trial was to evaluate colchicine compared with placebo administered within 30 days of a myocardial infarction. Study Design Randomized Parallel Double-blind Patients who suffered a myocardial infarction within the last 30 days were randomized to colchicine 0.5 mg daily (n = 2,366) versus placebo (n = 2,379). Total number of enrollees: 4,745 Duration of follow-up: median 22.6 months Mean patient age: 61 years Percentage female: 20% Percentage with diabetes: 20% Inclusion criteria:...