Separated item and exit doors for calcium keep energy production smooth in the powerhouses of heart cells
(PHYSorg.com Medicine & Health)

Stress demands the heart to work harder and faster. To keep pace, the muscle must make its fuel at an accelerated rate. Bursts of calcium entering mitochondria-the cell`s powerhouses-normally help control energy output, but too much calcium can overload the system and lead to cell death. Now research led by Jefferson (Philadelphia University + Thomas Jefferson University) scientist Gyorgy Csordas shows how mitochondria manage the flow of calcium to keep the engine running smoothly.