Scanning thousands of molecules against an elusive cancer target
(PHYSorg.com Chemistry)

Researchers at the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health, have developed a system to accelerate the discovery of chemical compounds that inhibit an enzyme implicated in a number of cancers. The set of tools and methods, which the researchers used to test more than 16,000 compounds, is described in a new paper published in the Journal of Biological Chemistry.