Patients` individual genomes may affect efficacy, safety of gene editing
(WorldNews Health)

Gene editing has begun to be tested in clinical trials, using CRISPR-Cas9 and other technologies to directly edit DNA inside people`s cells, and multiple trials are recruiting or in planning. A new study raises a note of caution, finding person-to-person genetic differences that may undercut the efficacy of gene editing or, more rarely, cause potentially dangerous `off target` effects. It suggests that gene editing may need to be adapted to each patient`s genome. ......