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RSS FeedsResearchers watch in real time as fat-encased drug nanoparticles invade skin cells
(PHYSorg.com Nanotechnology)

 
 

19 october 2017 08:34:59

 
Researchers watch in real time as fat-encased drug nanoparticles invade skin cells
(PHYSorg.com Nanotechnology)
 


Some anti-cancer drugs are encapsulated to allow gradual release, spreading their effect over a longer time. For example, one formulation of the chemotherapy doxorubicin (the FDA-approved drug Doxil) encloses molecules of the drug in fatty nano-spheres called liposomes, which allows the drug to circulate longer in the blood. However, the use of liposome `capsules` often comes with side-effects. Unfortunately, liposomes often end up in skin cells, resulting in rash and even lesions. These side effects can be `dose-limiting,` meaning that the amount of medicine that can be used is limited by the severity of side-effects. If researchers could decrease the side-effects of liposome use, doctors could use higher doses of these drugs, perhaps leading to better cancer control.


 
45 viewsCategory: Science > Physics
 
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