Understanding the architectures of inner mitochondrial membrane proteins
(PHYSorg.com Chemistry)

Membrane proteins make up approximately a quarter of all gene products and are the targets of over 50 percent of all modern pharmaceutical drugs. The inner mitochondrial membrane (IMM) proteome plays a central role in maintaining mitochondrial physiology and cellular metabolism. Despite their importance, there has been no method to reveal the topology of mitochondrial membrane proteins in live cells, until now.