Cryo-electron microscopy achieves unprecedented resolution using new computational methods
(PHYSorg.com Chemistry)

Cryo-electron microscopy (cryo-EM)-which enables the visualization of viruses, proteins, and other biological structures at the molecular level-is a critical tool used to advance biochemical knowledge. Now Lawrence Berkeley National Laboratory (Berkeley Lab) researchers have extended cryo-EM`s impact further by developing a new computational algorithm that was instrumental in constructing a 3-D atomic-scale model of bacteriophage P22 for the first time.